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DR FEDERICA AMATI: How Weight Loss Drugs Can Rewire Your Brain

DR FEDERICA AMATI: How Weight Loss Drugs Can Rewire Your Brain

Great Company with Jamie Laing
Sep 8, 2026 1h 21m
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About this episode

<p>Dr Federica Amati is the Head Nutritionist at ZOE and author of The Appetite Reset, <a href="https://amzn.eu/d/0iodLEof" rel="noopener noreferrer" target="_blank">https://amzn.eu/d/0iodLEof.</a> She first came on the show back in 2024 and she completely blew my mind.</p><br><p>Now she's back…And this time, she's tackling weight loss drugs.&nbsp;</p><br><p>What started as a prescription treatment for diabetes has become a global cultural phenomenon, with millions now taking GLP-1s to lose weight.&nbsp;</p><br><p>Dr Federica reveals that people can eat up to 40% less food while taking these drugs, causing significant changes to their bodies. She also explains how they can rewire our brains, as well as the short and long term effects of taking them.&nbsp;</p><br><p>In this episode, she shares:&nbsp;</p><ul><li>How weight loss drugs really affect our bodies and minds&nbsp;</li><li>The connection between GLP-1s and addiction&nbsp;</li><li>How ‘skinny jabs’ are changing our supermarket shelves</li><li>Why young women may face unique long-term risks from GLP-1s</li></ul><p><br></p><p>This is a fascinating conversation about medication that’s changing the way we think about our health, our bodies, and our relationship with food.&nbsp;</p><br><p>Dr Federica Amati is Great Company.&nbsp;</p><br><p>You can buy Dr Federica’s latest book, The Appetite Reset <a href="https://amzn.eu/d/0iodLEof" rel="noopener noreferrer" target="_blank">HERE</a>!</p><br><p>If you enjoyed the show, you can also follow us:&nbsp;</p><p>Instagram - @greatcompanypodcast</p><p>TikTok - @greatcompanypodcast&nbsp;</p><p>Jamie - @jamielaing</p><br><p>And if you've got thoughts, questions and comments, you can email us at: greatcompany@jampotproductions.co.uk</p><br><p>THE CREDITS</p><p>Producer: Magda Cassidy</p><p>Assistant Producer: Issy Weeks-Hankins</p><p>Video: Josh Bennett</p><p>Senior Social Media Manager: Laura Coughlan</p><p>Audio: Rafi Amsili Geovannetti</p><br><p>Shot on Sony Cinema Line cameras FX6, FX2 with Sony G-Master lenses 16-35GM, 24-70GM</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

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